Progesterone (Vaginal gel)
Progesterone vaginal gel 8% is a hormone treatment applied directly into the vagina using a pre-filled applicator. It supports the luteal phase during IVF cycles and helps prevent miscarriage by maintaining adequate progesterone levels in early pregnancy.
| Active Ingredient | Progesterone gel 8% |
|---|
Description
What is progesterone vaginal gel?
Progesterone gel is a hormone gel applied directly inside the vagina. It delivers progesterone locally. This means the body absorbs it without passing through the digestive system first. It comes in a single-use applicator for precise dosing.
What does it contain?
The active ingredient is progesterone 8%, which gives the product its full name vaginal gel 8%. Each applicator contains a measured dose of micronised progesterone in a gel base. No other hormones are present.
Who makes it?
Progesterone vaginal gel 8% is manufactured by Emcure. Emcure produces hormone-based medicines used in fertility and gynaecology. They follow standard pharmaceutical production processes for hormone gels.
What is it used for?
Progesterone vaginal gel 8% is used to support the luteal phase during assisted reproduction, including IVF cycles. It is also given to women who do not produce enough progesterone naturally. Low progesterone in early pregnancy raises the risk of miscarriage or premature birth. This product helps keep levels stable.
How does it work?
Progesterone is a hormone the ovaries produce after ovulation. When ovarian production is low or absent, the gel supplies it directly through the vaginal wall. The hormone enters the bloodstream from there. It keeps the uterine lining thick enough to support implantation. It works the same way as the progesterone your body makes naturally.
When should I take it?
Your doctor will set the timing based on your treatment plan. In IVF cycles, it is usually started on the day of egg retrieval or embryo transfer. Do not adjust timing on your own. Timing directly affects how well the lining is prepared.
What dose should I take?
One applicator once daily is the dose most commonly prescribed for luteal support. In some cases a doctor may increase this to twice daily. Always follow the prescription. Do not increase or reduce the dose without speaking to your doctor first.
How do I apply it?
Insert the pre-filled applicator into the vagina and press the plunger slowly. Lying down for a few minutes after application helps the gel stay in place. Apply at the same time each day. This keeps progesterone levels consistent.
What are the side effects?
- Vaginal discharge or wetness: the gel base does not fully absorb and a small amount passes back out. This is normal. It does not mean the dose was lost.
- Breast tenderness: rising progesterone causes breast tissue to respond, the same way it does in the second half of a natural cycle. It usually settles after a few weeks.
- Bloating
- Headache
- Mood changes
- Spotting or light bleeding
- Dizziness
If you notice sudden chest pain, difficulty breathing, or severe leg pain and swelling, contact a doctor immediately. These are rare but need prompt attention.
Who should not take it?
Do not use progesterone vaginal gel 8% if you have a known or suspected hormone-sensitive cancer. It is also not suitable for women with undiagnosed vaginal bleeding or liver disease. If you have a known allergy to progesterone, do not use this product. Tell your doctor about any existing conditions before starting.
Anything useful to know before starting?
A lot of people ask whether the gel leaking out means the dose is not working. It does not. A small amount of gel residue passing back out is normal. The active ingredient absorbs through the vaginal wall before the base clears.
Store applicators at room temperature, away from heat and direct sunlight. Do not refrigerate unless the packaging specifically says to.
Where can I order it?
Progesterone vaginal gel 8% is available through Truechemists. Hormone gel prices vary by pack size so check the current listing for details.


