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Janumet XR


Active Ingredient

Metformin, Sitagliptin

Brand Name

Janumet XR


What is Janumet XR?

Janumet¬† XR 100/1000 is a combination medication used to treat type 2 diabetes and contains the active ingredient sitagliptin and metformin in combination. Type 2 diabetes is a medical condition that causes high levels of blood sugar leading to the body’s inability to effectively use insulin leading to the development of insulin resistance. Janumet 100/1000 is a that medication can help in maintaining healthy blood sugar levels. Janumet Buy Online at TrueChemists we ship for a cheap price.

What are Metformin and Sitagliptin?

Metformin is an oral medication prescribed to manage patients with high blood sugar and developed type 2 diabetes. The medication works by reducing the glucose level in the blood by reducing the glucose production in the liver and enhancing the body’s response to insulin. It is considered the first line of treatment for treating diabetes in patients who are obese or overweight.

Sitagliptin is another medication that is prescribed for treating type 2 diabetes, It helps in lowering high blood sugar levels. It belongs to a class of drugs called dipeptidyl peptidase-4 inhibitors. The medication works by increasing the levels of incretin hormone which stimulates the pancreas gland to release insulin and helps in reducing the production of glucose by the liver.

How does Janumet XR 100/1000 effectively reduce high blood sugar?

Janumet XR 100/1000 is a combination of two medications metformin and sitagliptin. The dual action of this medication has a combinational effect on high blood glucose levels in patients with type 2 diabetes. Metformin works by reducing glucose production in the liver and improves the body’s sensitivity towards insulin. Sitagliptin helps in stimulating insulin release. Together these medicines result in better blood sugar control and address the insulin resistance and lower insulin production by the pancreas. It is suggested to have regular monitoring of blood sugar levels. Buy Janumet XR in USA for a low price at TrueChemists.


This medication is manufactured in India by MSD which is a brand of pharmaceutical pioneer Merck.

Mechanism of action

Sitagliptin 100 is a dipeptidyl peptidase-4 inhibitor, it prevents the breakdown of incretin hormones which are responsible for insulin secretion in the blood. By enhancing the insulin release, this medication can help you in a better management of high blood sugar levels in the blood. Metformin, when combined with sitagliptin, makes Janumet 100/1000 a powerful medication that uses a dual approach in addressing high blood sugar levels in patients with type 2 diabetes.


This medication is prescribed to patients to maintain healthy blood sugar levels in patients with type 2 diabetes which causes high blood sugar levels. It is also suggested to have a healthy balanced diet with exercise included to help in controlling healthy blood sugar levels.

Side effects?

Some of the side effects are

  • Nausea
  • Abdominal pain
  • Pain and discomfort in the stomach
  • Risk of low blood sugar levels (always carry a healthy source of snacks with you)
  • Upper respiratory tract infection
  • Vomiting
  • Diarrhea
  • Lactic acid buildup in blood
  • Difficulty breathing
  • Irregular heartbeat

Dosage recommendation

The recommended dosage is one tablet of Janumet either in 100/1000 or 100/1000. You should take it as prescribed by your doctor if they have asked you to take it before a meal then take it before a meal, if they have asked you for food, take it with food. You should always take your diabetes medicine at the same time daily and avoid missing your dosage. If you have missed your dose, take it as soon as you remember do not miss your dose for a longer duration.

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Overdose and double-dose

Do not take more than the recommended dosage as this medicine is not a cure for the condition but helps in the management of your type 2 diabetes. Remember taking more than the recommended dosage can cause serious effects including hypoglycemia also known as low blood sugar levels.

Suggestions and consideration

  • This combinational medication can cause effects on the kidneys, so it is suggested to have regular kidney function tests (every 3/6 months)
  • Increased lactic acid in the blood may cause kidney problems, and liver disease and may lead to heart failure.
  • Metformin has shown fewer to no effects in pregnancy but sitagliptin may cause effects therefore, you should stop taking this medication during pregnancy and you should share about it with your doctor.

How to store?

  • Store your medication in a cool and dry place away from direct heat and light.
  • Do not store near sources of heat like Sunlight, or microwaves.
  • This medication is not for children and it should be kept away from them.

Where to buy Janumet XR?

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