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Active Ingredient

Estradiol Valerate

Brand Name



Progynova 1 mg – 28 tablet/s, Progynova 2 mg – 28 tablet/s



What is Progynova 2 mg?

Progynova is an oral hormone pill. Available in 1mg and 2mg, it is used by women in hormone replacement therapy. The active ingredient is Estradiol valerate. Progynova 2mg is prescribed to patients with menopause symptoms in these conditions most women face hot flashes, bone loss, vaginal dryness, and low libido. The condition arrises when the female sex organ ovaries are unable to produce an effective amount of estradiol hormone. Progynova tablet is given in such therapy to treat menopause symptoms and improve the living quality in women. Buy Progynova 2 mg Online at TrueChemists.

What are the benefits of Progynova 2mg tablet?

Progynova 2 mg is prescribed to women who are suffering from painful symptoms related to menopause. Conditions like Hot flashes, affect the body temperature during menopause, reduce estrogen levels, and affect the working of the organs which includes the hypothalamus the region in the brain that regulates and controls the body temperature. As a result of bringing down temperature body produces sweat and increased heartbeat to dilate the blood vessels to help cool down the body.


Progynova 2 mg is also used in women patients who are suffering from menopause and have Bone loss (osteoporosis) a condition where the body loses bone cells over the period during the menopause phase. This happens due to an imbalance in cells responsible for removing dead cells of bone and producing new bone cells. During menopause, lower estrogen causes a hormonal imbalance where the body produces fewer bone cells and keeps on absorbing the bone cells leading to bone loss. With the help of Estradiol Valerate the loss of cells is restored and new cells keep on producing thus treating menopause.

Estradiol valerate tablets are also used in

  • Pregnancy maintains a healthy hormone balance which is essential for maintaining a healthy pregnancy.
  • Treat symptoms of Ovarian failure.
  • Used in severe cases of prostate cancer.
  • Treating fertility-related problems in female patients.
  • Stops the thinning of tissues in the urethra.
  • Treats decreased libido in women patients during menopause.
  • Stops hair fall in ladies during menopause.
  • Preventing osteoporosis
  • Increases lubrication in the vagina.

How does estradiol hormone work?

Estradiol valerate is the active ingredient in the progynova 2 mg tablets which are oral tablets that are prescribed to woman patients to treat menopausal symptoms. In pregnancy, these tablets are prescribed in fertility treatments such as IUI (intrauterine insemination) and IVF. In IVF it treats conditions to support the development and maintenance of endometrium and the uterus lining which is essential for the implantation and early pregnancy. Thin uterine lining can lead to pregnancy miscarriage and premature baby birth in some cases.

When a patient takes progynova 2mg, it keeps the lining intact and prevents shrinkage. The hormone estradiol is the hormone produced in the ovaries that keeps the lining thick when there is a lack of production of the hormone in the ovaries loss of pregnancy is overcome with the help of estradiol valerate hormone tablets.

During menopause, women patients are given these tablets to improve the overall hormone imbalance to prevent hot flashes, vaginal dryness, irritation, and bone loss. It improves bone density and regulates the periods which have become irregular over some time. Purchase Progynova 2 mg for your HRT in the USA.

How to use Progynova 2mg?

In IVF the dosage is one tablet twice daily with milk once in the morning with food and once in the evening during dinner. But dosage changes from patient to patient as each pregnancy case is unique. This tablet can also be taken by keeping under the tongue the proprietary formula of Bayer Pharmaceuticals making it a sublingual tablet that gets absorbed in the mouth without requiring to be swallowed as a whole tablet.

For treating patients with menopause symptoms, progynova 2mg is given as part of hormone replacement therapy. In this therapy, women patients are prescribed external forms of hormones to help maintain the healthy hormone balance essential for keeping estrogens in balance. The dosage varies from patient to patient and you should follow your doctor’s advice and information. You can take it with or without food and do not consume it with alcohol or aerated drinks which can cause lower effectiveness of the medicine. Always follow your doctor’s prescription carefully to ensure healthy effects and fewer side effects.

Side effects?

  • Abnormal uterine bleeding.
  • Headache
  • Mood swings
  • White discharge from the breast
  • Breast tenderness
  • Formation of blood clots
  • Upset stomach
  • Diabetes
  • Depression
  • Urge to cough
  • Loss of appetite
  • Bloating
  • Anxiety
  • Depression
  • Bloating
  • Redness
  • Body rashes

Long-term effects of Progynova 2mg?

Hormone replacement therapy is prescribed for a short time frame. Some women patients are prescribed for 2 to 5 years according to their symptoms, the severity of symptoms, and their condition which is different in every patient. But it’s suggested for the shortest possible duration. As long term usage can cause long-lasting painful effects such as

  • Ovarian cancer
  • Breast cancer
  • Blood clot
  • Deep vein thrombosis
  • Pain in breast
  • Lumps in breast
  • White discharge from the breast
  • Bloating
  • Edema
  • Stroke

Missed dose and overdose

If you have missed your dose, then take your missed dose of progynova 2 mg as soon as possible and avoid taking the double dose and overdosing if it’s time to take the next dosage. Make sure you keep your medicines handy and use mobile apps to set up reminders to help you remember medicine so that you never miss your dosage.

How long do you need to take Progynova 2mg tablets?

The duration of dosage is different in every condition. In pregnancy, it is prescribed in the initial pregnancy phase to prevent the uterine lining from shrinking. For HRT its dosage can be for a few days to provide relief from the menopause symptoms and may extend till a few months. Therefore you have to follow your doctor’s prescription carefully.


Stop taking the medication if

  • You are pregnant and your doctor has asked you to stop.
  • You have started breastfeeding or breastfeeding your child. Estradiol hormone is water soluble and gets dissolved in breast milk, therefore you should stop taking the medicine.
  • Having cancer
  • Clot formation in blood
  • Recent medical procedure
  • You have a heart and liver condition.
  • Having a cardiovascular disease
  • Hypertension should share about their condition before taking this medicine

Treating prostate cancer with estradiol hormone

  • If a male patient is advised Progynova 2 mg to treat prostate cancer. The medication works by shrinking and reducing the size of the prostate cancer. It stops the spread of the cancer to the other organs. But it has some serious side effects which include the formation of breasts, fat redistribution causing feminization, sexual dysfunction, permanent impotence, and permanent, irreversible changes to your sexual organ.

Efficacy and effectiveness?

Efficacy may reduce if you are taking any of the medication such as anticonvulsants, antivirals, or antitubercular drugs.

Why do transgender use progynova 2mg?

Transgender women individuals often advised estradiol by endocrinologists as part of hormone replacement therapy (HRT) for several reasons:


Progynova develops Female Secondary Sexual Characteristics such as

  • Breast Development: Estradiol promotes the growth of breast tissue, leading to the development of breasts.
  • Progynova causes fat to redistribute to areas more similar to a female body, such as hips, thighs, and buttocks.
  • Estradiol makes the skin softer and less oily, contributing to a more feminine appearance.
  • Reduction of Body Hair on the face, and body and promotes hair growth on the scalp.

Psychological Benefits Mental and Emotional Well-being

Hormone therapy with estradiol has been shown to improve mood and overall mental health for many transgender individuals. It can reduce gender dysphoria, a condition where there is significant distress.

Drug interactions

Medicines that can affect the effectiveness of the Progynova 2mg tablets are

How to store it?

Store it in a cool and dry place after taking the dose, and the pack of progynova 2mg tablets back to its carton. This will keep it away from direct heat and light which can cause reduced efficacy of the estradiol valerate tablets. Also available in the topical form of estradiol 0.06%

Where to buy progynova 2mg online?

Buy Progynova 2mg online at TrueChemists. Available in both 1 mg and 2mg tablets, the price starts at $0.30 per tablet. We ship Progynova 2 mg tablets in the USA in discrete packaging directly to your shipping address and in PO Boxes.